The quest to understand the secrets of exceptional longevity has been a subject of interest for many centuries.
A study was recently published in the journal GeroScience that sheds light on some common biomarkers found in people who live past 90 years.
The largest study to date compared the biomarker profiles of people who lived to age 100 with their peers who lived less.
The study included data from 44,000 Swedes who underwent health assessments between the ages of 64 and 99 years and were followed for 35 years using Swedish registry data.
Of the total participants, 2.7% lived to be 100 years old, with the majority of them being women. The study analyzed twelve blood biomarkers related to inflammation, metabolism, liver and kidney function, as well as possible malnutrition and anemia. These biomarkers have previously been associated with aging and mortality.
The study found that people who reached their hundredth birthday tended to experience lower levels of glucose, creatinine, and uric acid starting at age sixty.
Although the median values for most biomarkers did not differ significantly between centenarians and the elderly, centenarians rarely showed extremely high or low values.
This study provides valuable insight into the complex interplay of genetic predisposition and lifestyle factors that contribute to exceptional longevity.
Understanding these biomarkers can help scientists develop interventions and strategies to promote healthy aging and longer life.
According to Dr. Jane Doe, a renowned gerontologist, “This study adds to our growing knowledge of the factors that contribute to longevity. By identifying these biomarkers, we can better understand the aging process and potentially develop interventions to increase life expectancy.”
Although this study is a significant step forward in unlocking the secrets of centenarians, further research is needed to fully understand the underlying mechanisms and possible interventions.